LSD is usually swallowed or dissolved under the tongue, but it can also be sniffed, injected or smoked.1, 2 Show
Effects of LSDThere is no safe level of drug use. Use of any drug always carries some risk. It’s important to be careful when taking any type of drug. LSD can affect everyone differently, based on:
The effects of LSD usually begin in approximately 30 minutes and will last around 8-12 hours.5 The following may be experienced:
OverdoseIf someone takes a large amount, the negative effects of LSD are more likely. Call an ambulance straight away by dialling triple zero (000) if you or someone else has any of these symptoms (ambulance officers don’t need to involve the police):
Bad tripsSometimes a person can experience a ‘bad trip’, involving a disturbing hallucination. This can lead to panic and risky behaviour, like running across a road or attempting self-harm.1, 2 Coming downIn the following days after using LSD, the following may be experienced:
Long-term effectsSome people who regularly use LSD may eventually experience flashbacks. This is when an LSD experience reoccurs usually a visual distortion that involves perceptual or emotional changes. Flashbacks can happen weeks, months or even years after the drug was last taken. Flashbacks can be disturbing, especially if a frightening experience or hallucination is recalled.1, 2 Flashbacks can be brought on by stress, tiredness, exercise or using other drugs. They usually last for a minute or two.2 LSD and Mental HealthUsing LSD can trigger or worsen mental health problems such as anxiety, schizophrenia or psychosis.1, 2 Anyone with a history of these issues should avoid using LSD. However, research into the administration of LSD in a safe, therapeutic setting, involving a controlled dose, has shown positive results in treating depression, post-traumatic stress disorder, and reducing anxiety in patients with a life-threatening disease.6 Read more about some of this research. Tolerance and dependenceTolerance develops rapidly to the effects of LSD. After the third or fourth consecutive days of taking LSD, no amount of the drug can produce the desired effects. However, after a short period of abstinence (about three to four days), tolerance should return to normal.2 Mixing LSD with other drugsThe effects of taking LSD with other drugs − including over-the-counter or prescribed medications − can be unpredictable and dangerous, and could cause:
‘Polydrug use’ is a term for the use of more than one drug or type of drug at the same time, or one after another. Polydrug use can involve both illicit drugs and legal substances, such as alcohol and medications. Find out more about polydrug use. WithdrawalThere are no known physical withdrawal symptoms of LSD. Taking LSD regularly does not result in physical dependence. While there have been reports of psychological dependence, the evidence is limited.1, 2
LSD (lysergic acid diethylamide) is a hallucinogenic drug. Hallucinogens change the way people sense the world around them. Sometimes Called:acid, sugar cubes, white lightning, dose, tripping, blotter How It's Used:LSD is odorless, colorless, and tasteless. It can be painted onto small squares of paper that people lick or swallow. What It Does:LSD causes the senses of space, distance, and time to become altered. People say they "hear" colors or "see" sounds, and have strange feelings and strong emotions. Many users refer to an "acid trip" — when the effects don't let up and can last for up to 12 hours at a time. LSD also can cause "bad trips" — when users experience panic, confusion, sadness, and scary images. Bad reactions can happen with the first use and a user may have flashbacks later, experiencing the feelings of a bad trip even after the drug wears off. Because LSD also affects judgment and behavior, users might find themselves in a dangerous situation. Physical changes include increased heart rate and blood pressure, muscle twitches and shaking, dilated pupils, sweating, sleeplessness, and loss of appetite.
D-lysergic acid diethylamide, better known as LSD or “acid,” is a hallucinogenic drug made from lysergic acid, a natural chemical found in a fungus that grows on rye called Claviceps purpurea. LSD was first created in 1938 by a Swiss chemist named Albert Hoffmann who was searching for new drugs to stimulate patients’ circulation and breathing. Dr. Hoffmann discovered LSD’s striking mental effects in 1943, and the drug was marketed under the brand name Delysid from 1947 to 1966. It was used to enhance the effectiveness of psychotherapy and to treat psychiatric illnesses such as depression and alcohol addiction. Starting in the 1950s, the United States Central Intelligence Agency and the Army conducted experiments to find out if LSD could be a useful tool for exerting “mind control” on enemies 1. Recreational use of LSD began in the 1960s and spread rapidly until the drug was banned in 1970 by categorizing it as a Schedule I drug under the Controlled Substances Act. As a schedule I drug, LSD has no recognized medical use and those caught in possession of it face serious legal penalties. Is LSD (Acid) Bad For You?LSD (acid) can cause persistent psychological problems that cause significant distress to the user. Alongside psychological risks, LSD can also have physical risks and both short term and long term side effects. LSD is generally considered to be less harmful than other drugs like alcohol, heroin, and cocaine, and overdoses are rare. 2,3.4 5 As with many drugs of abuse, young men may appear to be disproportionately impacted by the dangers of LSD—of the 5,000 emergency room visits in 2011, 84% were male and 70% were between 18 and 24 years old.5 Side Effects of LSD (Acid)The side effects of acid are similar to other hallucinogens. LSD is active mainly at certain serotonin receptor sub-types in the brain and body. Serotonin is a neurotransmitter involved with activation of the sympathetic nervous system, which is responsible for your body’s “fight or flight” reaction 3. LSD’s Short-Term EffectsPeople generally use acid and other classic hallucinogens such as psilocybin (magic mushrooms) and peyote (mescaline) for recreational and spiritual reasons 2. These drugs are also known as “psychedelics” and produce temporary symptoms similar to psychosis that typically last between 6 and 10 hours 2. These altered perceptions and sense of unreality are commonly called a “trip” and may result in 3,7:
People who develop HPPD, also known as “flashbacks,” have repeated experiences with symptoms similar to an LSD trip even when they have not taken the drug again. These symptoms include hallucinations and other visual distortions such as halos or trails on moving objects 7. Symptoms of HPPD can last from weeks to years before resolving on their own, and there is no widely recognized treatment 8. In some cases, HPPD is severe, long-lasting, and has a significant negative effect on other aspects of a user’s life. The distressing effects of a bad trip normally ease when the drug wears off; however, it can persist for weeks or months in some users 2. These long-term side effects are known by the clinical terms “Persistent Psychosis” and “Hallucinogen Persisting Perception Disorder (HPPD)” 5. Such complications are rare, but can happen after using LSD just one time. Individuals who abuse LSD over a long period 1 or have a history of abusing multiple drugs may also be at greater risk of developing these conditions8. Individuals suffering from Persistent Psychosis can have visual disturbances, disorganized thinking, paranoia, and mood disturbances that continue long after the last use of the drug. While this condition is not well understood 7, symptoms are sometimes managed with antidepressants or antipsychotics.
LSD (acid) does carry some health risks and side-effects. By interfering with normal serotonin signaling, LSD produces both the short-term effects mentioned above as well as the following negative side effects 4; 5:
LSD Psychological RisksIn addition to presenting physical risks, LSD has powerful effects on users’ mental states and can produce traumatic emotional reactions in some individuals, also called a “bad trip”. Symptoms of a bad trip can feel overwhelming to the user and may include the following 3:
Taking acid in an uncontrolled setting or taking a larger dose than expected increases the danger of having a bad trip 2; 6. LSD abusers with a personal or family history of psychosis or other severe psychiatric disorders are also thought to be at greater risk of having a bad trip or developing other psychological problems 7. Abusers having a bad trip can behave in unpredictable ways that present a danger to themselves and others. LSD OverdoseBecause LSD is one of the most potent drugs known, extremely small doses of this drug can produce noticeable effects. A “typical” dose of LSD ranges between 75 and 150 micrograms (millionths of a gram) 2. This is about 3,000 times less than the amount of aspirin in a regular-strength tablet. Because LSD is made illegally, there are large differences in the amount of drug in different batches, making it very easy to accidentally take a dose larger than intended. The greatest danger of taking too much LSD is that it will trigger a bad trip or other psychological trauma 6. Despite the psychological danger posed by LSD overdose, this drug has a low toxicity, and the amount needed to produce a dangerous physical reaction is very large. In fact, there has never been a recorded case of a human dying from an LSD overdose, although it has proven fatal in studies on animals 1. In the rare cases that people have accidentally ingested massive overdoses of LSD, the symptoms have included 2: LSD DependenceThe scientific evidence indicates that LSD does not produce dependence and is not addictive. However, tolerance to the effects of LSD develops very quickly, meaning that frequent use of the drug will result in diminished effects over time. Essentially, the same dose won’t create the same “high.” Some users may increase the dose of LSD they take to overcome this tolerance, which can increase the risk of experiencing the negative effects discussed above. Compulsive LSD users may also develop a pattern of problematic use defined as a hallucinogen use disorder by the American Psychiatric Association. Signs include:
Despite the lack of evidence supporting a classic picture of physiologic dependence and addiction development, people can still be profoundly and negatively impacted by frequent LSD use, and could benefit from some sort of substance abuse treatment intervention. LSD Withdrawal TreatmentEven in individuals who have taken LSD chronically for a long period of time, there are usually no withdrawal symptoms when they stop, and there are no FDA-approved medications available to treat LSD withdrawal 7. However, the intense effects LSD has on perceptions, moods, and thoughts may cause ongoing psychological distress that may lead to impaired functioning in the user’s life, and drug treatment programs or professional psychological support may be beneficial to abusers who want to stop. Little is known about treating hallucinogen abuse, and more research is needed. Currently, there are no specific treatments for LSD abuse, and general strategies such as counseling and cognitive-behavioral therapy are used to change problematic behaviors and support sobriety. Check if Your Insurance Covers LSD Addiction TreatmentLearn more about insurance coverage levels from some household health brand names for LSD addiction rehab and treatment: Related Resources
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