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Bulk laxatives
 Dietary fiber, psyllium, polycarbophil, methylcellulose, carboxymethylcellulose
Osmotic agents
 Saline laxatives: Magnesium, sulfate, potassium and phosphate salts
 Poorly absorbed sugars: Lactulose, sorbitol, mannitol, lactose, glycerine suppositories
 Polyethylene glycol (PEG): PEG 3350 laxative
Stimulant laxatives
 Surface-active agents: Docusate, bile salts
 Diphenylmethane derivatives: Phenolphthalein, bisacodyl, sodium picosulfate
 Ricinoleic acid: Castor oil
 Anthraquinones: Senna, cascara sagrada, aloe, rhubarb
 Mineral oil
Neuromuscular agents
 5-HT4 Agonists: Cisapride, norcisapride, prucalopride, tegaserod
 Prostaglandin agent: Misoprostol
 Cholinergic agents: Bethanechol, neostigmine
 Opiate antagonists: Naloxone, naltrexone
Investigational agents
 Recombinant methionyl human brain-derived neurotrophic factor (r-metHuBDNF), neurotropin-3